What is Cialis and its uses

Formula: C22H19N3O4

Molar mass: Pharmacokinetic data

Bioavailability: Varies

Protein binding: 94%

Metabolism: Liver (predominantly CYP3A4)

Metabolites: Catechol metabolite

Elimination half-life: 17.5 hours

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What is Cialis?
Cialis is a medicine which used for erectile dysfunction treatment for men. It is when a man cannot get or sustain a hard, erect penis sufficient for sexual activity. The capacity to acquire a hard erect penis for sexual intercourse has been shown that substantially increase by Cialis.

Cialis requires a drug named phosphodiesterase Type 5 inhibitor, called the active agent tadalafil. Cialis acts to enable the blood vessels in the penis to relax and blood flow to the penis after sexual stimulation. As a result, erectile function is increases in body . If you have no erectile dysfunction, then Cialis not improve anything.

Description

Cialis (tadalafil) is a selective phosphodiesterase type 5 inhibitor of cyclic guanosine monophosphate (cGMP) (PDE5). Tadalafil has a C22H19N3O4 analytical formula which is 389.41 molecular in weight.

The chemical is nearly insoluble crystalline solid in water and extremely lighter in ethanol soluble.

For oral administration, Cialis is available as an almond shaped tablet. The inactive ingredients of tadalafil in each tablet are 2.5, 5, 10 and 20 mg: croscarmellose, hydroxypropyl cellulose, iron oxide, lactose monohydrate, magnesium stearate, magnesium stearate, microcrystalline cellulose, sodium lauryl sulphate, talc, titanium dioxide and triacetin.

Tadalafil is used in treatment for erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension that is labelled with the Cialis brand name among others . It is a tablet taken in the mouth. Usually, the occurrence of Tadalafil takes half an hour, and it is normally up to 36 hours .
Caution is advised in people with cardiovascular disease.. Tadalafil is not advised for those taking nitro vasodilators, such as nitroglycerin because it may result in an extreme drop in blood pressure,The effect is not recommended for those taking nitro vasodilators .

Erectile dysfunction

FDA approved Tadalafil is sold for Erectile Dysfunction once daily with strengths of 2,5, 5, 10 and 20 mg. The price of five mg and two and a half mg is always close, so that people divide the pill .
Hypertrophy of the benign prostatic
Tadalafil 5 mg meta‐analysis shown that taking once a day can be an effective treatment for lower urinary tract symptoms caused by prostatic hyperplasia and to be low in adverse events. Tadalafil 10 mg is approved as a once-a-daily treatment of men for FDA for the treatment and prevention of symptoms such as urinary emergency, delay, poor streams and dribbling of benign prostatic hypertrophy (PFH).

Uses

Tadalafil is used to treat male issues with sexual activity (impotence or erectile dysfunction-ED). Tadalafil works by increasing the blood flow to your penis in conjunction with sexual stimulation to help a person get and sustain erection.
The symptoms of an enlarged prostate are also treated by tadalafil (benign prostatic hyperplasia-BPH). It contributes to reduce BPH symptoms such as trouble starting urine flow, sluggish stream and urination (including during the middle of the night). Tadalafil is intended to function in the prostate and bladder by calming the smooth muscle.
This medicine does not prevent sexually transmitted diseases (such as HIV, hepatitis B, gonorrhea, syphilis).

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